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active centre

British  

noun

  1. Also called: active sitebiochem the region in an enzyme molecule in which the reactive groups that participate in its action are juxtaposed

"Collins English Dictionary — Complete & Unabridged" 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

Example Sentences

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In this regard, Destroyer makes an interesting companion piece to Steve McQueen and Gillian Flynn’s sharp, angry update of Lynda La Plante’s Widows – another bleak, hard-boiled genre piece to unusually place a fiftysomething woman at the active centre of its copious action.

From The Guardian

By 1700 Boston had already overtaken Oxford and Cambridge to become the second most active centre of publishing of English books after London.

From BBC

Under the Sassanian kings, Persia had become an active centre of intellectual life, reaching the climax of its Augustan age in the reign of Chosroes.

From Project Gutenberg

It is now a very active centre of iron and steel manufactures.

From Project Gutenberg

No more urgent necessity had ever arisen than this present, and One-Tree Pass for once in its life became the active centre of the island.

From Project Gutenberg